The Center for Implementation researches and actively contributes to the implementation of effective interventions and quality standards. The Center actively shares collected knowledge with health care institutions and other implementation research programs. Effective implementation efforts and research are the keys to translating research to practice to improve health outcomes.

Center for Implementation

As a research institution, the Trimbos Institute is involved in many research projects concerning the effectiveness of (preventive) interventions, as well as participating in the development of various quality standards. The Trimbos Institute is knowledgeable about effective tools to prevent problems related to alcohol, tobacco, and drugs, as well as tools for improving care for clients. However, it remains difficult to implement these effective tools on a large scale. A consequence is that the health benefits are smaller than expected. Often, this disparity is related to the implementation process. Even though information about which tools are effective with mental health problems and substance abuse is well-known, it remains difficult to translate this knowledge into practice. The Center for Implementation was established to address problems in implementing new health tools and programs, as well as to reduce the disparity between anticipated health outcomes and actual outcomes related to the implementation of programs.

Goals and aims

The Center for Implementation focuses on two goals:

  1. Researching and understanding how interventions and quality standards can be implemented on a large scale in ways that they are most effective.


  2. Implementing effective interventions and quality standards.

Staff and experts at the Center for Implementation research the processes involved in implementing programs, tools, and projects while also contributing to the national implementation of effective interventions and quality standards in the fields of mental health and addiction. The primary goal of the work of the Center is to improve health outcomes.

Researching the implementation process is a relatively new research domain. There are still questions about what is necessary to translate research into practice with the aim of improving the health of the entire society. Attitudes such as “we should do what works”, and “we need to invest more money” are not always the correct answers.

Questions such as “Why do professionals not always comply to quality standards?” or “Why do municipalities invest money in ineffective projects?” are only a fraction of the many questions that need to be answered before we know how implementation can be done effectively.

In the coming years, the Center for Implementation will focus on the following themes:

  1. Making implementation research more attractive for investors;
  2. Performing implementation research in collaboration with care institutions; and
  3. Disseminating the results of implementation research and sharing knowledge.


One of the primary roles of the Center is implementing effective interventions in mental health and addiction care. The Trimbos Institute has decades of experience when it comes to implementing projects; one ongoing, large-scale example is the Healthy School prevention program. This program has been in place for over 20 years and has and improved the health of many children. This program and study, as well as other projects conducted by the Trimbos Institute, have aided the Center in understanding what makes implementation effective. Armed with this knowledge, it is now possible to implement more effective interventions and make substantial gains in health.

In the coming years, the Center for Implementation will focus on the following implementation targets:

  • Ensuring that effective interventions and quality standards are performed on a large scale among the target group, and
  • Assuring that implementation processes are a mandatory topic in the development of new interventions and quality standards.

The Center uses well-known methods to study implementation processes and improve health delivery programs; these methods include Intervention Mapping, the Breakthrough Method, the Triple Aim method, and the Plan-Do-Study-Act cycle.


Working with organizations

The Center for Implementation works for various organizations such as national and local governments, health insurers, research investors, healthcare institutions, and branch organizations. Anyone who has questions concerning how effective interventions and quality standards can be implemented at a large scale in their domain is welcome at the Center for Implementation. We are happy to think with you!

The Center for Implementation supports the Network of Quality Development Mental Health Sector Netwerk Kwaliteitsontwikkeling GGz in Dutch) and is involved as co-founder of the Dutch Implementation Collective (Nederlands Implementatie Collectief in Dutch).

The Center's Profile

To characterize the Center for Implementation and to increase its visibility, a one-minute animation was developed to highlight the Center’s goals, aims, added value, and future development. Currently, there are many interventions and quality standards not yet implemented, because there has been little effort to implement effective interventions on a large scale, and many questions about approaches for effective implementation remain. The Center is working towards increasing the implementation of effective interventions.

Selected publications

Sinnema H, Majo MC, Volker D, Hoogendoorn A, Terluin B, Wensing M, Balkom A van. Effectiveness of a tailored implementation programme to improve recognition, diagnosis and treatment of anxiety and depression in general practice: a cluster randomised controlled trial. Implementation Science, Implementation Science , 10, (pp. 33).

Hermens M, Oud M, Sinnema H, Nauta M, Stikkelbroek Y, Duin D, Wensing M. The multidisciplinary depression guideline for children and adolescents: an implementation study. European Child & Adolescent Psychiatry. 2015 Jan 15.